Motor Neurons Tune Premotor Activity in a Vertebrate Central Pattern Generator

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Motor Neurons Tune Premotor Activity in a Vertebrate Central Pattern Generator.

Central patterns generators (CPGs) are neural circuits that drive rhythmic motor output without sensory feedback. Vertebrate CPGs are generally believed to operate in a top-down manner in which premotor interneurons activate motor neurons that in turn drive muscles. In contrast, the frog (Xenopus laevis) vocal CPG contains a functionally unexplored neuronal projection from the motor nucleus to ...

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The central pattern generator for heartbeat in medicinal leeches constitutes seven identified pairs of segmental heart interneurons. Four identified pairs of heart interneurons make a staggered pattern of inhibitory synaptic connections with segmental heart motor neurons. Using extracellular recording from multiple interneurons in the network in 56 isolated nerve cords, we show that this patter...

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A central pattern generator producing alternative outputs: phase relations of leech heart motor neurons with respect to premotor synaptic input.

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ژورنال

عنوان ژورنال: The Journal of Neuroscience

سال: 2017

ISSN: 0270-6474,1529-2401

DOI: 10.1523/jneurosci.2755-16.2017